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Gear Guides/Best Baby Formula
Similac 360 Total Care Infant Formula
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Similac 360 Total Care Infant Formula

Similac's flagship milk-based formula with a full slate of HMO prebiotics for parents who want the loaded option.

85
NewMom Index
85 / 100
Price range $$$
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The verdict

Similac 360 Total Care is Enfamil's main rival and a great pick if your baby is already on Similac or your hospital uses it. It's a standard milk-based formula boosted with five HMO prebiotics (structurally similar to some found in breast milk) plus lutein and vitamin E, and it's just as widely stocked and easy to mix. It's a genuine upgrade in the sense of 'more added ingredients,' but the practical difference over a basic formula is modest, so don't feel behind if you use something simpler. Skip it if you want organic, if your baby has a diagnosed cow's-milk allergy, or if you're pinching pennies, since store brands cover the same essentials for less.

What we love
  • Contains five HMO prebiotics, more than most competitors
  • Widely available and hospital-familiar
  • Mixes easily and comes in multiple formats
  • Adds lutein and vitamin E alongside DHA
Keep in mind
  • Premium price for benefits that are incremental at best
  • Conventional (non-organic) milk-based formula
  • Marketing leans hard on the 'closer to breast milk' angle
Is the Similac 360 Total Care Infant Formula right for you?
Parents who want the most fully-loaded mainstream milk-based formula and don't mind paying for it.